Actualidades en el tratamiento de la hipertensión arterial sistémica en el paciente con diabetes.
DOI:
https://doi.org/10.58713/rf.v1i2.4Palabras clave:
Diabetes, Hipertensión arterial, AntihipertensivosResumen
La hipertensión arterial sistémica (HAS) y la diabetes mellitus (DM) son enfermedades crónico-degenerativas que lideran las causas de morbimortalidad en el mundo debido a sus complicaciones cardiovasculares. Ambos padecimientos comparten aspectos fisiopatológicos que explican la frecuencia de su asociación, tales como el incremento del estrés oxidativo, reducción de la biodisponibilidad del óxido nítrico, elevación de citocinas proinflamatorias, alteraciones en la regulación del sistema nervioso autónomo y del sistema renina-angiotensina- aldosterona que conducen a un incremento de grasa visceral, resistencia a la insulina y vasoconstricción. Los fármacos que se utilizan para el tratamiento de la HAS pueden tener efectos en la homeostasis de la glucosa, mismos que deben ser tomados en cuenta al momento de la prescripción.
El presente documento tiene la finalidad de presentar las recomendaciones más actualesqueabordaneltratamientodela HAS en sujetos con DM.
Citas
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